Food Biofortification—Reaping the Benefits of Science to Overcome Hidden Hunger

Authors

  • Howarth Bouis International Food Policy Research Institute image/svg+xml Author
  • Ekin Birol HarvestPlus Author
  • Erick Boy HarvestPlus Author
  • Bryan Gannon Cornell University image/svg+xml Author
  • Jere Haas Cornell University image/svg+xml Author
  • Jan Low International Potato Center image/svg+xml Author
  • Saurabh Mehta Cornell University image/svg+xml Author
  • Kristina Michaux HarvestPlus Author
  • Bho Mudyahoto HarvestPlus Author
  • Wolfgang Pfeiffer HarvestPlus Author
  • Matin Qaim University of Göttingen image/svg+xml Author
  • Chelsea Reinberg HarvestPlus Author
  • Torbert Rocheford Purdue University Author
  • Alexander J. Stein European Commission image/svg+xml Author
  • Simon Strobbe Ghent University image/svg+xml Author
  • Dominique Van Der Straeten Ghent University image/svg+xml Author
  • Vincent Verbeecke Ghent University image/svg+xml Author
  • Ross Welch Cornell University image/svg+xml Author

DOI:

https://doi.org/10.62300/wwprsm34

Keywords:

Biofortification, Micronutrient Deficiencies, Staple Crop Nutrition, HarvestPlus Program, Cost-Effective Nutrition Interventions

Abstract

Micronutrient deficiencies affect more than two billion people worldwide, particularly in low‑ and middle‑income countries (LMICs), where dietary quality is limited by low consumption of nutrient‑dense foods. Biofortification—enhancing the vitamin and mineral content of staple crops through conventional breeding, agronomic practices, or genetic engineering—offers a cost‑effective and sustainable strategy to address this “hidden hunger.” This paper synthesizes nearly two decades of evidence from the HarvestPlus program and partner institutions on the development, bioavailability, efficacy, and large‑scale dissemination of biofortified crops. Controlled feeding trials consistently demonstrate that biofortified varieties of beans, pearl millet, rice, maize, cassava, and sweet potato provide significantly more absorbable iron, zinc, and provitamin A than conventional counterparts, improving micronutrient status and, in some cases, cognitive and physical performance. More than 340 biofortified varieties have been released across 40 countries, with more than 15 million farming households growing them. Delivery models and demand‑creation strategies—especially for visible traits such as provitamin A carotenoids—have shown high consumer acceptance. Cost‑effectiveness analyses indicate that biofortification often delivers greater health impact per dollar than many standard nutrition interventions. The paper also evaluates future scientific opportunities, including improved biomarkers, enhanced bioavailability traits, and the role of transgenic and genome‑editing technologies in advancing multi‑nutrient biofortification. Integrating biofortification into national policies, seed systems, and food value chains is essential for achieving resilient, nutrition‑smart food systems capable of improving diets sustainably, particularly in the context of climate change and global health disruptions such as COVID‑19.

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Food Biofortification—Reaping the Benefits of Science to Overcome Hidden Hunger

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2020-10-14

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Bouis, H., Birol, E., Boy, E., Gannon, B., Haas, J., Low, J., Mehta, S., Michaux, K., Mudyahoto, B., Pfeiffer, W., Qaim, M., Reinberg, C., Rocheford, T., Stein, A. J., Strobbe, S., Van Der Straeten, D., Verbeecke, V., & Welch, R. (2020). Food Biofortification—Reaping the Benefits of Science to Overcome Hidden Hunger. Council for Agricultural Science and Technology (CAST). https://doi.org/10.62300/wwprsm34

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